Jeffrey Silber, MD, PhD, Co-Investigator; Economic Impact of Clinical Trials for Childhood Cancers

Jeffrey Silber, MD, PhD, is Co-Investigator on the UPenn PRC Economic Impact of Clinical Trials on Childhood Cancers Project. Dr. Silber is Director of the Center for Outcomes Research (COR) at the Children’s Hospital of Philadelphia (CHOP). He helped to establish COR in 1997 and has served as Director since its inception. He is also the Nancy Abramson Wolfson Endowed Chair in Health Services Research at CHOP, Professor of Pediatrics, Anesthesiology, and Critical Care at the Perelman School of Medicine at the University of Pennsylvania and Professor of Health Care Management at the Wharton School at the University of Pennsylvania.

Dr. Silber is an internationally known authority on outcomes measurement and severity adjustment for both adult and pediatric applications. He created the adult quality of care measure Failure-to-Rescue (FTR) in 1992 that has been adopted as three specific quality measures by the National Quality Forum (NQF) and also developed two length of stay outcome measures: Prolonged Length of Stay and Conditional Length of Stay. He has published extensively on all aspects of the theory of outcomes measure and model development and validation, as well as the applications of outcomes measures to pressing public health issues.  Much of his recent work focuses on the use of multivariate matching when comparing outcomes, specifically with respect to problems in both pediatric and adult medicine and surgery, disparities, and cancer. Dr. Silber has twice been awarded the Article of the Year Award in Health Services Research from AcademyHealth, the leading professional organization concerning Health Services Research in the U.S. His current research interests include the development of new health care outcome measures, statistical methodology in outcomes research including multivariate matching, clinical economics, measuring health care quality, health care disparities, medical decision making and outcomes of care in cancer.  He earned an MD from the Johns Hopkins School of Medicine in 1980 and a PhD in Health Care Management (formerly Health Care Systems) at the Wharton School at the University of Pennsylvania in 1990.

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