Jason Karlawish, MD, is Principal Investigator on the UPenn PRC Cognitive Aging Project and Healthy Brain Research Network. Dr. Karlawish is a Professor of Medicine, Medical Ethics and Health Policy at the University of Pennsylvania, Perelman School of Medicine. He is board-certified in geriatric medicine. Dr. Karlawish is a Senior Fellow of the Leonard Davis Institute of Health Economics; a fellow of the University of Pennsylvania's Institute on Aging; Director of the Penn Neurodegenerative Disease Ethics and Policy Program; Associate Director of the Penn Memory Center; Director of the Alzheimer's Disease Center's Outreach, Recruitment and Education Core; and Director of the Penn Prevention Research Center's Healthy Brain Research Center, part of the CDC supported Healthy Brain Research Network dedicated to surveillance, education, awareness and empowerment that promotes brain health. He is also the project leader of https://makingsenseofalzheimers.org/, a creative space for understanding the past, present and future of Alzheimer’s disease. Utilizing multi-media formats such as slideshows, video, and audio clips, along with written stories, the site explores the changing understandings of what Alzheimer’s is and how this affects our ethics and ideas of personhood. His research focuses on ethical and policy issues related to cognitive impairment, particularly on Alzheimer’s disease and other neurodegenerative disorders. He has investigated issues in Alzheimer’s disease drug development, decision-making capacity, quality of life, decision-making in research and treatment, and voting by persons with cognitive impairment. His current work examines the ethical, legal and social issues encountered in research to validate a “preclinical” or “prodromal” stage of Alzheimer’s disease. To learn more, visit: jasonkarlawish.com.